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Intrathecal Morphine for Recovery and Outcomes After VATS
Sponsor: Ataturk University
Summary
This study will compare two different methods of pain management in patients undergoing video-assisted thoracoscopic surgery (VATS). One group will receive a combination of spinal morphine, nerve block, and dexmedetomidine, while the other group will receive a nerve block and dexmedetomidine without spinal morphine. All patients will receive standard pain medications after surgery. The purpose is to see if adding spinal morphine improves pain control and recovery after surgery.
Official title: The Effects of Intrathecal Morphine in Addition to Serratus Anterior Plane Block and Dexmedetomidine on Postoperative Recovery (QoR-15) and Systemic Inflammation in Video-Assisted Thoracoscopic Surgery: A Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
52
Start Date
2025-12-01
Completion Date
2026-06-02
Last Updated
2026-02-05
Healthy Volunteers
No
Interventions
Intrathecal Morphine
200 µg morphine sulfate, single-dose via L3-L4, 27G Sprotte spinal needle, prior to induction.
Serratus Anterior Plane Block (SAPB) group
Ultrasound-guided unilateral SAPB at end of surgery with 30 mL 0.25% bupivacaine.
Dexmedetomidine
Loading dose 0.5 µg/kg over 15 minutes, then 0.5 µg/kg/h continuous infusion intraoperatively.
Locations (2)
Ataturk University
Erzurum, Turkey (Türkiye)
Ataturk University
Erzurum, Turkey (Türkiye)