Clinical Research Directory
Browse clinical research sites, groups, and studies.
A Study to Evaluate How the Study Drug Moves Through the Body, Adverse Events, and How the Body Tolerates ABBV-547 Injections
Sponsor: AbbVie
Summary
The purpose of this study is to assess how safe, effective, and tolerable ABBV-547 is in adult participants in the United States and Japan. There will be 2 parts to this study. In Part 1, participants are placed in one of 7 groups where they will receive ABBV-547 at different doses or placebo. There is a 1 in 4 chance participants will receive placebo. In Part 2, participants are placed in one of 3 groups where they will receive ABBV-547 at different doses or placebo. There is a 1 in 7 chance participants will receive placebo. Approximately 121 adult participants will be enrolled at approximately 21 sites in the United States and Japan. Participants will be administered one dose of ABBV-547 or placebo. There may be higher treatment burden for participants in this trial compared to their standard of care. Participants will attend regular visits during the study at a hospital or clinic. The effect of the treatment will be checked by medical assessments, blood tests, checking for side effects and completing questionnaires.
Official title: A First-in-Human, Phase 1a/b, Single-Dose Study of ABBV-547 to Evaluate the Pharmacokinetics, Immunogenicity, Safety, and Tolerability in Adult Participants and Efficacy in Adult Participants
Key Details
Gender
All
Age Range
18 Years - 55 Years
Study Type
INTERVENTIONAL
Enrollment
121
Start Date
2025-11-24
Completion Date
2027-08
Last Updated
2026-06-17
Healthy Volunteers
Yes
Conditions
Interventions
ABBV-547
Parental Administration
ABBV-547 Placebo
Parental Administration
Locations (23)
Total Dermatology /ID# 279798
Birmingham, Alabama, United States
Dermatology Trial Associates /ID# 279984
Bryant, Arkansas, United States
Cenexel act- Anaheim Clinical Trials /ID# 279612
Anaheim, California, United States
Dermatology Research Associates - Los Angeles /ID# 279383
Los Angeles, California, United States
Integrative Skin Science and Research - Location 2 /ID# 279386
Sacramento, California, United States
Skin Care Research Boca Raton /ID# 279988
Boca Raton, Florida, United States
Wellness Clinical Research - Miami Lakes /ID# 279803
Miami Lakes, Florida, United States
Advanced Clinical Research Institute - Tampa /ID# 279342
Tampa, Florida, United States
Trueblue Clinical Research - Tampa /ID# 281757
Tampa, Florida, United States
University Dermatology & Vein Clinic - Darien /ID# 279986
Darien, Illinois, United States
Acpru /Id# 278638
Grayslake, Illinois, United States
MetroBoston Clinical Partners /ID# 279992
Boston, Massachusetts, United States
Minnesota Clinical Study Center /ID# 279987
New Brighton, Minnesota, United States
MediSearch Clinical Trials /ID# 279416
Saint Joseph, Missouri, United States
Skin Specialists /ID# 279531
Omaha, Nebraska, United States
The Skin Center Dermatology Group /ID# 279983
New City, New York, United States
Equity Medical, LLC - Bronx /ID# 279808
The Bronx, New York, United States
Oregon Dermatology & Research Center /ID# 279391
Portland, Oregon, United States
Health Concepts /ID# 279529
Rapid City, South Dakota, United States
Center for Clinical Studies - Houston - Binz Street /ID# 279419
Houston, Texas, United States
Austin Institute for Clinical Research - Pflugerville /ID# 279387
Pflugerville, Texas, United States
University of the Ryukyus Hospital /ID# 279918
Ginowan-shi, Okinawa, Japan
Fukuoka University Hospital /ID# 279530
Fukuoka, Japan