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A Study of the Effect of Diltiazem on the Plasma Levels of Nemtabrutinib (MK-1026-022)
Sponsor: Merck Sharp & Dohme LLC
Summary
The goal of the study is to learn what happens to levels of nemtabrutinib (MK-1026) in a healthy person's body over time. Researchers will compare what happens to nemtabrutinib in the body when it is given with or without another medicine called diltiazem.
Official title: A Study to Evaluate the Effect of Multiple Oral Doses of Diltiazem on the Single-Dose Pharmacokinetics of Nemtabrutinib in Healthy Participants.
Key Details
Gender
All
Age Range
18 Years - 55 Years
Study Type
INTERVENTIONAL
Enrollment
24
Start Date
2025-12-08
Completion Date
2026-05-16
Last Updated
2026-04-08
Healthy Volunteers
Yes
Conditions
Interventions
Nemtabrutinib
Oral administration
Diltiazem
Oral administration
Locations (1)
Fortea CRU Madison ( Site 0001)
Madison, Wisconsin, United States