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NOT YET RECRUITING
NCT07234422
PHASE3

The SELEQT-HF (SELEnium and CoQ10 NuTrition for Heart Failure) Study Will Evaluate the Effect of Adding Selenium/and coQ10 on Top of Standard HF Therapy in Patients With HF and Will do so Using a Pragmatic, Registry Based Randomized Controlled Trial in the Netherlands.

Sponsor: Netherlands Heart Institute

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to learn whether taking selenium and coenzyme Q10 (CoQ10) can reduce HF related events and deaths related to cardiovascular disease. Researchers will compare selenium-CoQ10 supplements with a placebo to see if the supplements improve heart health and patient outcomes. Participants will: Receive either selenium-CoQ10 or placebo in addition to their usual heart failure treatment Attend standard clinical visits according to routine clinical care. The study will include 1,100 adults with chronic heart failure. Selenium and CoQ10 are natural nutrients with no known health risks. If effective, this supplement could provide a safe new way to improve outcomes for people with heart failure.

Official title: A Registry-Based Randomised Controlled Trial With Heart 4 Data - SELEnium and CoQ10 NuTrition for Heart Failure: H4D-SELEQT-HF

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

1100

Start Date

2026-05-01

Completion Date

2030-12

Last Updated

2026-04-08

Healthy Volunteers

No

Conditions

Interventions

DIETARY_SUPPLEMENT

Selenium/CoQ10

Oral dosage of twice daily Selenium/CoQ10 (2 x 100 μg selenium tablets (SelenoPrecise 100 μg, Pharma Nord, Denmark) and 2 x 100 mg Q10 capsules (Bio-Quinon 100 mg B.I.D, Pharma Nord, Denmark)

DRUG

Matching Placebo (B)

Matching Placebo

Locations (7)

Noordwest Ziekenhuisgroep

Alkmaar, Netherlands

AUMC

Amsterdam, Netherlands

Amphia Ziekenhuis

Breda, Netherlands

Catharina ziekenhuis Eindhoven

Eindhoven, Netherlands

TREANT

Emmen, Netherlands

University Medical Center Groningen

Groningen, Netherlands

St Antonius ziekenhuis

Nieuwegein, Netherlands