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ENROLLING BY INVITATION
NCT07238049

REAl World Dementia OUTcomes: Observational Study

Sponsor: University of Oxford

View on ClinicalTrials.gov

Summary

READ-OUT observational study will investigate blood-based biomarkers for dementia in real-world clinical settings. This 3-year observational study will include 3165 people, males or females aged 45 years or older, with cognitive impairment of any severity. Participants provide blood samples and complete questionnaires about quality of life and healthcare use, with some having additional follow-ups at 2 weeks and 1 year. The study will assess reliability and accuracy of blood tests in diagnosing dementia.

Official title: READ-OUT - REAl World Dementia OUTcomes: Observational Study

Key Details

Gender

All

Age Range

45 Years - Any

Study Type

OBSERVATIONAL

Enrollment

3165

Start Date

2024-11-01

Completion Date

2029-10-31

Last Updated

2025-11-20

Healthy Volunteers

No

Locations (27)

Betsi Cadwaladr University Health Board

Bangor, United Kingdom

ReMind UK

Bath, United Kingdom

Belfast Health & Social Care Trust

Belfast, United Kingdom

Dorset HealthCare University NHS Foundation Trust

Bournemouth, United Kingdom

Berkshire Healthcare NHS Foundation Trust

Bracknell, United Kingdom

Bradford District Care NHS Foundation Trust

Bradford, United Kingdom

North Bristol NHS Trust

Bristol, United Kingdom

Cambridgeshire and Peterborough NHS Foundation Trust

Cambridge, United Kingdom

Devon Partnership NHS Trust

Exeter, United Kingdom

Barts Health NHS Trust

London, United Kingdom

East London NHS Foundation Trust

London, United Kingdom

South London and Maudsley (SLaM)

London, United Kingdom

St George's Hospital

London, United Kingdom

West London NHS Trust

London, United Kingdom

Greater Manchester Mental Health Foundation Trust

Manchester, United Kingdom

Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust

Newcastle upon Tyne, United Kingdom

Aneurin Bevan University Health Board

Newport, United Kingdom

Nottingham University Hospitals NHS Trust

Nottingham, United Kingdom

Oxford Health NHS Trust

Oxford, United Kingdom

Lancashire & South Cumbria NHS Foundation Trust

Preston, United Kingdom

Surrey and Borders Partnership NHS Foundation Trust

Redhill, United Kingdom

Sheffield Health and Social Care NHS Foundation Trust

Sheffield, United Kingdom

Sheffield Teaching Hospital

Sheffield, United Kingdom

Hampshire and Isle of Wight NHS Foundation Trust

Southampton, United Kingdom

University Hospital Southampton

Southampton, United Kingdom

Midlands Partnership University NHS Foundation Trust

Stafford, United Kingdom

Sussex Partnership NHS Foundation Trust

Worthing, United Kingdom