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NCT07238426

ATTRACT-52: Primary Care Cardiac Amyloidosis Screening in Ordu, Turkey

Sponsor: Kotyora Family Medicine Health Management and Education Association

View on ClinicalTrials.gov

Summary

Cardiac amyloidosis is a progressive infiltrative cardiomyopathy, most commonly related to transthyretin (ATTR) misfolding. Although considered rare, emerging data suggest higher prevalence in specific regions, including the Black Sea area of Turkey. Early recognition improves outcomes. ATTRACT-52 is a prospective, observational, non-interventional screening study in primary care (family medicine centers) across Ordu province. Adults ≥65 years with cardiac or musculoskeletal "red flags" will be screened; those meeting high-suspicion criteria will undergo NT-proBNP/BNP testing at the primary care level to aid risk stratification prior to referral for confirmatory diagnostics.

Official title: ATTRACT-52: Advancing TTR Testing and Risk-Based Amyloidosis Cardiac Screening in Primary Care - The Ordu Pilot Study

Key Details

Gender

All

Age Range

65 Years - Any

Study Type

OBSERVATIONAL

Enrollment

800

Start Date

2025-12-01

Completion Date

2026-10-31

Last Updated

2026-02-25

Healthy Volunteers

No

Locations (1)

Ordu University Faculty of Medicine, Department of Cardiology

Ordu, Ordu, Turkey (Türkiye)