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Beta-lactam Plus Levofloxacin to Enhance Therapy in Streptococcal Septicemia
Sponsor: Mahidol University
Summary
A double-blind randomized controlled trial comparing beta-lactam plus levofloxacin versus beta-lactam monotherapy for the treatment of Streptococcal bacteremia
Official title: Beta-lactam Monotherapy Versus Beta-lactam Plus Levofloxacin for the Treatment of Streptococcal Bacteremia: A Multicenter, Randomized, Double-Blind, Pragmatic Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
165
Start Date
2026-01-01
Completion Date
2028-12-31
Last Updated
2025-11-20
Healthy Volunteers
No
Conditions
Interventions
Beta-lactam monotherapy
Normal saline placebo
Beta-lactam plus levofloxacin combination therapy
IV Levofloxacin
Locations (4)
Faculty of Medicine Siriraj Hospital
Bangkok, Thailand
Maharaj Nakorn Chiang Mai Hospital
Chiang Mai, Thailand
Maharaj Nakhon Ratchasima
Nakhon Ratchasima, Thailand
Ratchburi Hospital
Ratchaburi, Thailand