Clinical Research Directory
Browse clinical research sites, groups, and studies.
Xylitol Gum for Promoting Smoking Cessation
Sponsor: The University of Hong Kong
Summary
The goal of this clinical trial is to learn if 4-week xylitol gum intervention works to promote smoking cessation in daily smokers. It will also learn about the feasibility and acceptability of using xylitol gum. The main questions it aims to answer are: （1）Does xylitol gum help to reduce cigarette consumption and promote smoking cessation? Researchers will compare 4-week xylitol gum intervention to the brief advice to see if xylitol gum works to promote smoking cessation. Participants in the intervention group will receive a 3-month behavioral intervention comprising a 4-week xylitol gum aligned with 12 weeks of instant reminder message support.
Official title: The Effectiveness of Chewing Gum for Reducing Cigarette Consumption and Promoting Smoking Cessation: A Pilot Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
134
Start Date
2025-11-24
Completion Date
2026-09-30
Last Updated
2025-11-21
Healthy Volunteers
No
Conditions
Interventions
Brief smoking cessation advice
Brief smoking cessation advice guided by the validated AWARD model (Assess, Warning, Advice, Refer, and Do-it-again).
Warning leaflet
The warning leaflet contains pictorial depictions of the adverse health effects of smoking.
Self-help smoking cessation booklet
The self-help smoking cessation booklet includes commonly used smoking cessation strategies.
4-week xylitol gum intervention
Participants in the intervention group will receive 4 packs of xylitol gum (approximately US $2 per pack) at baseline and will be encouraged to use it when they experience cravings.
Instructional leaflet
The instructional leaflet includes the potential benefits of xylitol gum for smoking cessation, recommended timing and dosage for use, and appropriate disposal of used gum.
12-week instant message support
Approximately 24 reminder messages (two per week), developed based on the Love and Care Approach framework, will be delivered over the 12-week period to reinforce motivation and adherence.
Locations (1)
School of Nursing, The University of Hong Kong
Hong Kong, Hong Kong