Clinical Research Directory

Detection of Minimal Residual Disease Using Exosomal miRNA Distant Metastasis Markers

Sponsor: City of Hope Medical Center

Summary

Gastric cancer (GC) is a leading cause of cancer-related death worldwide. Even in patients undergoing curative surgery for non-metastatic disease, postoperative recurrence frequently occurs due to undetected minimal residual disease (MRD). This study aims to establish a highly sensitive and specific liquid biopsy assay using exosomal microRNAs (exo-miRNAs) to detect MRD and predict distant metastasis before clinical recurrence.

Official title: Exosomal microRNA-based Analysis for Early detectIon of Gastric Cancer Hidden-recurrence Traces

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