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Tumor-Derived Extracellular Vesicles for Noninvasive Molecular Classification of Kidney Cancer
Sponsor: Mayo Clinic
Summary
This is a correlative (lab-based) study aiming to identify protein markers in urine extracellular vesicles (EVs) that can be used to develop non-invasive molecular tests for patients with renal cell carcinoma (RCC). Aim 1 will use urine collected previously in biorepository. Aim 2 will prospectively collect blood specimens pre and post nephrectomy.
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
300
Start Date
2026-07-15
Completion Date
2027-04-30
Last Updated
2026-02-27
Healthy Volunteers
No
Conditions
Interventions
Proteomic profiling of urinary EVs
EV isolation and mass spectrometry.
Blood sample collection
Blood samples collected pre- and post-nephrectomy
Locations (1)
Mayo Clinic in Rochester
Rochester, Minnesota, United States