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RECRUITING
NCT07244211
NA

MAPT Protocol: Fixation Versus Arthroplasty Surgical Treatments for Early Recovery After HIP Fracture (FASTER-HIP)

Sponsor: University of Southern California

View on ClinicalTrials.gov

Summary

This study is an intervention domain of the Musculoskeletal Adaptive Platform Trial. The primary goal of this pragmatic, randomized, open-label, comparative effectiveness trial is to evaluate if arthroplasty is superior to internal fixation when used to treat minimally displaced femoral neck fractures in older adults ≥60 years old. We hypothesize that arthroplasty will reduce death, preserve ambulation, increase days alive and out of hospital, and improve health status compared to internal fixation within 4 months and 12 months from randomization.

Official title: Musculoskeletal Adaptive Platform Trial (MAPT): Fixation Versus Arthroplasty Surgical Treatments for Early Recovery After HIP Fracture (FASTER-HIP)

Key Details

Gender

All

Age Range

60 Years - Any

Study Type

INTERVENTIONAL

Enrollment

600

Start Date

2026-01-23

Completion Date

2030-01-31

Last Updated

2026-10-05

Healthy Volunteers

No

Interventions

PROCEDURE

Hip arthroplasty

Participants will undergo surgical treatment using standard hip arthroplasty techniques for femoral minimally displaced femoral neck fracture. A modern porous-coated press-fit or cemented hip arthroplasty prosthesis will be used at the treating surgeon's discretion. Press-fit implants that have no ingrowth or ongrowth surface will not be permitted. The type of hip prosthesis (hemiarthroplasty or total hip arthroplasty), bearing (single or dual mobility), or the method of arthroplasty fixation (cemented or uncemented) will be at the discretion of the treating surgeon.

PROCEDURE

Internal fixation

Participants will undergo surgical treatment using standard fixation techniques for minimally displaced femoral neck fractures. The treating surgeon may perform fracture reduction maneuvers if desired. Fixed-angle devices and multiple screws will be permitted. The internal fixation device(s) will be inserted through a small lateral incision. Internal fixation constructs combining cancellous screws and fixed-angle devices will be permitted.

Locations (31)

University of California, Irvine

Irvine, California, United States

Los Angeles General Medical Center

Los Angeles, California, United States

University of Southern California

Los Angeles, California, United States

Cedars-Sinai Medical Center

Los Angeles, California, United States

University of California San Francisco

San Francisco, California, United States

University of Miami

Miami, Florida, United States

Indiana University

Bloomington, Indiana, United States

University of Maryland, Baltimore - R Adams Cowley Shock Trauma Center

Baltimore, Maryland, United States

University of Maryland Capital Region Health

Largo, Maryland, United States

Beth Israel Deaconess Medical Center

Boston, Massachusetts, United States

University of Mississippi

University, Mississippi, United States

NYU Langone Health

New York, New York, United States

University of Cincinnati

Cincinnati, Ohio, United States

University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, United States

St. Luke's University Health System

Allentown, Pennsylvania, United States

Prisma Health-Upstate

Greenville, South Carolina, United States

Vanderbilt University

Nashville, Tennessee, United States

University of Utah

Salt Lake City, Utah, United States

University of Vermont

Burlington, Vermont, United States

Inova Health Care Services

Fairfax, Virginia, United States

University of Wisconsin - Madison

Madison, Wisconsin, United States

University of British Columbia

Vancouver, British Columbia, Canada

Fraser Health Authority

Vancouver, British Columbia, Canada

London Health Sciences Centre

London, Ontario, Canada

The Ottawa Hospital

Ottawa, Canada

Sykehuset Østfold HF / Østfold Hospital Trust

Grålum, Norway

Hospital Universitario Mutua de Terrassa

Barcelona, Spain

Consorci Sanitari de l'Alt Penedès i Garraf (CSAPG)

Barcelona, Spain

FRCB-IDIBAPS (Hospital Clinic Barcelona)

Barcelona, Spain

Hospital Universitari Vall d'Hebron

Barcelona, Spain

University of Edinburgh

Edinburgh, United Kingdom