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NOT YET RECRUITING
NCT07245147
NA

REDO-AF: Randomized Evaluation of Dual Options for AF Re-intervention

Sponsor: Jacqueline Joza

View on ClinicalTrials.gov

Summary

The goal of this randomized open-label clinical trial is to evaluate two different strategies for the treatment of recurrent atrial fibrillation (AF) after AF ablation. Patients who have symptomatic, drug-refractory recurrence of AF will be randomized to either a redo AF ablation vs conduction system pacing with AV node ablation. Patients will need to have undergone at least 1 prior AF ablation to be considered eligible for the study. The current trial is a vanguard study of 16 patients and will determine the feasibility of enrolment, compare changes in quality of life, and inform the design of the definitive REDO AF trial.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

16

Start Date

2025-11

Completion Date

2027-09

Last Updated

2025-11-24

Healthy Volunteers

No

Interventions

PROCEDURE

Redo AF Ablation

Redo AF Ablation as per operator discretion

PROCEDURE

Pace and Ablate

Left bundle branch pacing with AV node ablation

Locations (1)

McGill University Health Center

Montreal, Canada