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REDO-AF: Randomized Evaluation of Dual Options for AF Re-intervention
Sponsor: Jacqueline Joza
Summary
The goal of this randomized open-label clinical trial is to evaluate two different strategies for the treatment of recurrent atrial fibrillation (AF) after AF ablation. Patients who have symptomatic, drug-refractory recurrence of AF will be randomized to either a redo AF ablation vs conduction system pacing with AV node ablation. Patients will need to have undergone at least 1 prior AF ablation to be considered eligible for the study. The current trial is a vanguard study of 16 patients and will determine the feasibility of enrolment, compare changes in quality of life, and inform the design of the definitive REDO AF trial.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
16
Start Date
2025-11
Completion Date
2027-09
Last Updated
2025-11-24
Healthy Volunteers
No
Interventions
Redo AF Ablation
Redo AF Ablation as per operator discretion
Pace and Ablate
Left bundle branch pacing with AV node ablation
Locations (1)
McGill University Health Center
Montreal, Canada