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LVT DURATION: Pilot Study of Anticoagulation Duration for Left Ventricular Thrombus
Sponsor: Queen Mary University of London
Summary
The LVT DURATION (Optimal Duration of Anticoagulation for LV Thrombus) is a pilot study planned to assess the practicalities of conducting a randomised control trial (RCT) whilst establishing data around the ideal duration of anticoagulation in the treatment of LV thrombus. The main objectives of the study are: * To assess the practicalities of conducting an RCT with regard to recruitment, retention, and outcome measurement. * To identify the optimal length of anticoagulation in the treatment of LV Thrombus After randomisation participants will: * Continue their prescribed oral anticoagulant for the remainder of the trial * Discontinue their prescribed oral anticoagulant for the remainder of the trial
Official title: A Randomised Pilot Study Assessing the Optimal Duration of Anticoagulation for Left Ventricular Thrombus
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
120
Start Date
2026-12-01
Completion Date
2027-12-01
Last Updated
2026-02-27
Healthy Volunteers
No
Conditions
Interventions
Continue rivaroxaban or apixaban or warfarin
The study is asessing the impact of discontinuation of oral anticoagulation in patients with LV thrombus diagnosis.
Discontinue rivaroxaban or apixaban or warfarin
discontinue rivaroxaban or apixaban or warfarin
Locations (1)
St Bartholomews Hospital
London, United Kingdom