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IPP Placement & Intracavernosal Block
Sponsor: Wake Forest University Health Sciences
Summary
The inflatable penile prosthesis (IPP) is the gold standard for surgical management of erectile dysfunction (ED) and there is no consensus on the best postoperative pain management regimen. In the wake of the opioid epidemic, postoperative pain management is heavily scrutinized. The National Institute of Health estimated over 81,000 individuals died following overdose of any opioids in 2022 alone; of these, over 14,000 deaths were linked to prescription opioids. Thus, strategies to minimize postoperative pain should not only improve patient experience but also lessen the need to escalate to opioid usage.
Official title: Randomized Controlled Trial of Intracorporal Local Anesthesia vs Saline Prior to Placement of Inflatable Penile Prosthesis Placement
Key Details
Gender
MALE
Age Range
21 Years - Any
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2026-05
Completion Date
2027-10
Last Updated
2026-03-31
Healthy Volunteers
No
Conditions
Interventions
Exparel/bupivacaine mixture
10cc of Exparel (133 mg, 1.3%) with 10cc of 0.5% standard bupivacaine (50 mg )for total volume of 20cc into the corpora immediately prior to placement of corporotomy stay sutures.
Locations (1)
Wake Forest University Health Sciences
Winston-Salem, North Carolina, United States