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Lignin in Treatment of Helicobacter Pylori Infection
Sponsor: Zagazig University
Summary
The goal of this clinical trial is to learn if drug hydrolyzed lignin works to treat H pylori infection in adults. It will also learn about the safety of drug lignin n the sitting of H pylori infection, and if it halts the side effects associated with H pylori triple therapy. The main questions it aims to answer are: * Does drug hydrolyzed lignin improve the H pylori eradiation rate when it is added to the standard triple therapy used in treatment of H pylori? * What medical problems do participants experience when taking drug hydrolyzed lignin? Researchers will compare drug hydrolyzed lignin to a placebo (a look-alike substance that contains no drug) to see if drug hydrolyzed lignin works to treat H pylori. Participants will: * Take drug hydrolyzed lignin or a placebo every day for 2 weeks beside the standard triple therapy * Visit the clinic once every 1 week for checkup and questionnaire filling * Check for H pylori eradication after treatment
Official title: Role of Lignin in Treatment of Helicobacter Pylori Infection: A Double-blind Placebo-controlled Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
70
Start Date
2025-10-31
Completion Date
2026-03-15
Last Updated
2025-11-24
Healthy Volunteers
No
Conditions
Interventions
Hydrolyzed Lignin
The drug will be supplied randomly to the group I
Placebo
Will be supplied randomly to Group II
Locations (1)
Kafrelsheikh University
Kafr ash Shaykh, Kafr el-Sheikh Governorate, Egypt