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ACTIVE NOT RECRUITING
NCT07246681
PHASE3

Lignin in Treatment of Helicobacter Pylori Infection

Sponsor: Zagazig University

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to learn if drug hydrolyzed lignin works to treat H pylori infection in adults. It will also learn about the safety of drug lignin n the sitting of H pylori infection, and if it halts the side effects associated with H pylori triple therapy. The main questions it aims to answer are: * Does drug hydrolyzed lignin improve the H pylori eradiation rate when it is added to the standard triple therapy used in treatment of H pylori? * What medical problems do participants experience when taking drug hydrolyzed lignin? Researchers will compare drug hydrolyzed lignin to a placebo (a look-alike substance that contains no drug) to see if drug hydrolyzed lignin works to treat H pylori. Participants will: * Take drug hydrolyzed lignin or a placebo every day for 2 weeks beside the standard triple therapy * Visit the clinic once every 1 week for checkup and questionnaire filling * Check for H pylori eradication after treatment

Official title: Role of Lignin in Treatment of Helicobacter Pylori Infection: A Double-blind Placebo-controlled Study

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

70

Start Date

2025-10-31

Completion Date

2026-03-15

Last Updated

2025-11-24

Healthy Volunteers

No

Interventions

DRUG

Hydrolyzed Lignin

The drug will be supplied randomly to the group I

OTHER

Placebo

Will be supplied randomly to Group II

Locations (1)

Kafrelsheikh University

Kafr ash Shaykh, Kafr el-Sheikh Governorate, Egypt