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Ketamine-lidocaine Versus Ketamine-fentanyl for Induction of Anesthesia in Patients With Left Ventricular Systolic Dysfunction Undergoing Elective Coronary Artery Bypass
Sponsor: Cairo University
Summary
This study compares ketamine/fentanyl versus ketamine/lidocaine in term of their impact on cerebral perfusion during CABG. No prior data address these effects, and the goal is to identify the induction regimen that better preserves cerebral oxygenation.
Official title: A Comparison Between the Effect of Ketamine-lidocaine Versus Ketamine-fentanyl for Induction of Anesthesia on Cerebral Perfusion Guided by Near Infra-red Spectroscopy in Patients With Coronary Artery Disease and Left Ventricular Systolic Dysfunction Undergoing Elective Coronary Artery Bypass Graft Surgery: (A Randomized Controlled Study)
Key Details
Gender
All
Age Range
21 Years - Any
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2025-12-01
Completion Date
2026-07
Last Updated
2026-03-17
Healthy Volunteers
No
Conditions
Interventions
Fentanyl (IV)
patients will receive 1 mcg/kg of Fentanyl (10 mcg/mL).
lidocaine
patients will receive 1 mg/kg lidocaine (10mg/mL)
Locations (1)
Kasr Alainy Hospital
Cairo, Egypt