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ENROLLING BY INVITATION
NCT07248891

Type 2 Diabetes and Associated Factors in Mexico

Sponsor: Coordinación de Investigación en Salud, Mexico

View on ClinicalTrials.gov

Summary

The goal of this observational cross-sectional multicenter study is to identify clinical, lifestyle, metabolic, inflammatory, and genetic factors associated with glycemic control and complications of Type 2 Diabetes (T2D) in adult patients in Mexico. The main questions it aims to answer are: Which molecular and clinical factors are associated with poor glycemic control (HbA1c \> 7%)? Which factors are linked to the presence of diabetic nephropathy (GFR \< 60 mL/min/1.73 m²)? Participants: Provide informed consent and clinical history. Undergo a clinical and physical evaluation (including six-minute walk test). Complete lifestyle, dietary, and therapeutic adherence questionnaires. Provide blood samples for biochemical, inflammatory, and transcriptomic (RNA-Seq) analysis. Researchers integrate clinical, biochemical, and transcriptomic data using statistical modeling to identify a characteristic molecular fingerprint of poor metabolic control and diabetes-related complications.

Official title: Comprehensive Study of Associated Factors With Type 2 Diabetes in Mexico: Protocol

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

1000

Start Date

2025-04-01

Completion Date

2025-12-30

Last Updated

2025-12-04

Healthy Volunteers

No

Interventions

OTHER

Clinical and Molecular Assessment

Participants underwent clinical examination, lifestyle and dietary questionnaires, functional testing (six-minute walk test), and blood sampling for biochemical and transcriptomic analysis.

Locations (3)

Coordinación de Investigación en Salud

Mexico City, Mexico City, Mexico

División de Investigación en Salud

Mexico City, Mexico City, Mexico

Instituto Mexicano del Seguro Social

Mexico City, Mexico City, Mexico