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Type 2 Diabetes and Associated Factors in Mexico
Sponsor: Coordinación de Investigación en Salud, Mexico
Summary
The goal of this observational cross-sectional multicenter study is to identify clinical, lifestyle, metabolic, inflammatory, and genetic factors associated with glycemic control and complications of Type 2 Diabetes (T2D) in adult patients in Mexico. The main questions it aims to answer are: Which molecular and clinical factors are associated with poor glycemic control (HbA1c \> 7%)? Which factors are linked to the presence of diabetic nephropathy (GFR \< 60 mL/min/1.73 m²)? Participants: Provide informed consent and clinical history. Undergo a clinical and physical evaluation (including six-minute walk test). Complete lifestyle, dietary, and therapeutic adherence questionnaires. Provide blood samples for biochemical, inflammatory, and transcriptomic (RNA-Seq) analysis. Researchers integrate clinical, biochemical, and transcriptomic data using statistical modeling to identify a characteristic molecular fingerprint of poor metabolic control and diabetes-related complications.
Official title: Comprehensive Study of Associated Factors With Type 2 Diabetes in Mexico: Protocol
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
1000
Start Date
2025-04-01
Completion Date
2025-12-30
Last Updated
2025-12-04
Healthy Volunteers
No
Interventions
Clinical and Molecular Assessment
Participants underwent clinical examination, lifestyle and dietary questionnaires, functional testing (six-minute walk test), and blood sampling for biochemical and transcriptomic analysis.
Locations (3)
Coordinación de Investigación en Salud
Mexico City, Mexico City, Mexico
División de Investigación en Salud
Mexico City, Mexico City, Mexico
Instituto Mexicano del Seguro Social
Mexico City, Mexico City, Mexico