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Lipopolysaccharide Adsorption (Efferon LPS NEO) in Children With Thermal Burns
Sponsor: Efferon JSC
Summary
This observational pilot study aims to identify criteria for evaluating the effectiveness of hemoadsorption with the Efferon LPS NEO device in pediatric burn injury. Participants will be prospectively assigned to the treatment group and compared with a retrospectively selected control group. Each patient in the treatment group will undergo two hemoadsorption sessions, each lasting 6-12 hours, with an interval of 24-120 hours between procedures. The sessions may be performed in combination with hemofiltration or hemodiafiltration at the discretion of the investigator.
Official title: An Observational Pilot Study Evaluating the Efficacy and Safety of LPS Adsorption Using the Efferon LPS NEO Device in Children With Thermal Burns
Key Details
Gender
All
Age Range
1 Year - 14 Years
Study Type
OBSERVATIONAL
Enrollment
30
Start Date
2025-10-01
Completion Date
2027-03-31
Last Updated
2025-11-25
Healthy Volunteers
No
Conditions
Interventions
Efferon LPS NEO
Efferon LPS NEO, a medical device, which is a cylindrical body filled with a polymeric hemosorbent that selectively absorbs LPS and excess cytokines. Two hemoadsorption procedures will be performed per patient, with a duration of 6-12 hours each and an interval of 24-120 hours between procedures. The procedures may be administered in combination with hemofiltration or hemodiafiltration, as determined by the investigator.
Locations (2)
Children's City Clinical Hospital No. 9 named after G.N. Speransky of the Moscow City Health Department
Moscow, Russia
Children's municipal multi-specialty clinical center of high medical technology
Saint Petersburg, Russia