Clinical Research Directory
Browse clinical research sites, groups, and studies.
The Use of Near-Infrared Fluorescence Cholangiography With Indocyanine Green (ICG) in the Work Up of Neonatal Cholestasis
Sponsor: University of Alabama at Birmingham
Summary
In infants that present with findings concerning for biliary atresia, along with other cholestatic work up which is standard, they will receive a one-time intravenous (IV) dose of Indocyanine Green (ICG). The infant's diapers will subsequently be examined for presence of the ICG, and if present, suggests bile flow. This was described as 97% accurate for assessing biliary patency and we would like to perform a similar study to assess biliary patency in the work up of neonatal cholestasis.
Key Details
Gender
All
Age Range
2 Weeks - 4 Months
Study Type
INTERVENTIONAL
Enrollment
15
Start Date
2026-01-23
Completion Date
2027-03
Last Updated
2026-02-18
Healthy Volunteers
Yes
Interventions
Indocyanine Green
Optical imaging agent
Locations (1)
University of Alabama At Birmingham
Birmingham, Alabama, United States