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Neoadjuvant Embolization and Cytoreduction in Prostate Cancer
Sponsor: Srinivas Raman
Summary
The goal of this clinical trial is to find out whether prostate artery embolization (PAE) can help prevent or lessen urinary side effects caused by radiotherapy (RT) in people with prostate cancer, especially those who have larger prostates or urinary symptoms before treatment. The main questions this study aims to answer are: * Does PAE before RT reduce the severity of urinary side effects from RT? * Does PAE affect the rates of genitourinary (GU) or gastrointestinal (GI) side effects after RT? Researchers will look at changes in urinary symptoms from the start of the study to 6 months after PAE. They will also record any GU or GI side effects related to RT. Participants will receive prostate artery embolization before starting radiotherapy, and complete questionnaires and assessments about GU and GI functions before and after treatment.
Official title: Neoadjuvant Embolization and Cytoreduction to Ameliorate Radiotherapy Toxicity in Prostate Cancer
Key Details
Gender
MALE
Age Range
Any - Any
Study Type
INTERVENTIONAL
Enrollment
35
Start Date
2026-02
Completion Date
2027-12
Last Updated
2025-11-26
Healthy Volunteers
No
Conditions
Interventions
Prostatic Artery Embolization
PAE is a minimally invasive procedure that involves embolizing the arteries supplying the prostate, leading to its shrinkage.