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Effect of Pentoxifylline + CoQ10 vs CoQ10 Alone on Sperm Motility in Subfertile Men With Asthenozoospermia
Sponsor: Mst.Sumyara Khatun
Summary
The goal of this clinical trial is to learn if drug Pentoxifylline plus Coenzyme Q10 work to treat asthenozoospermia in subfertile male. It will also learn about the safety of drug Pentoxifylline plus Coenzyme Q10. The main questions it aims to answer are: Does drug Pentoxifylline plus Coenzyme Q10 increase the motility of sperm in participants? What medical problems do participants have when taking drug Pentoxifylline plus Coenzyme Q10 ? Researchers will compare drug Pentoxifylline plus Coenzyme Q10 combination to Coenzyme Q10 alone to see if drug Pentoxifylline plus Coenzyme Q10 combination works better. Participants will: Experimental Group:Pentoxifylline 400mg twice dailyand Coenzyme Q10 100mg twice daily for 3 months. Comparator Group: Coenzyme Q10 100mg twice daily for 3 months Visit the clinic after three months of treatment for checkups and tests
Official title: Effect of Pentoxifylline Plus Coenzyme Q10 Combination Therapy Compared to Coenzyme Q10 Alone on Sperm Motility in Sub-fertile Male With Asthenozoospermia
Key Details
Gender
MALE
Age Range
20 Years - 50 Years
Study Type
INTERVENTIONAL
Enrollment
56
Start Date
2025-10-01
Completion Date
2027-03-01
Last Updated
2025-11-26
Healthy Volunteers
No
Conditions
Interventions
Coenzyme Q 10
Participants will receive Coenzyme Q10 100 mg twice daily for 3 months
Pentoxifylline 400 MG Oral Tablet
Participants will receive pentoxifylline 400mg twice daily plus coenzyme Q10 100mg twice daily for 3 months
Locations (1)
Bangladesh Medical University
Dhaka, Shahbag, Bangladesh