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Mouthwash Temperature and Oral Mucositis in Head and Neck Radiotherapy
Sponsor: Chung Shan Medical University
Summary
This single-center randomized controlled trial evaluates the effects of cold (15-20°C) versus room-temperature (30-35°C) water gargling on oral mucositis severity, pain, and comfort in patients with head and neck cancer undergoing radiotherapy. Participants will rinse their mouth four times daily for 30-60 seconds over a 6-week radiotherapy course, with follow-up for two additional weeks. The study hypothesizes that cold-water rinsing can reduce the severity of radiation-induced oral mucositis (RTOM) and pain, improve oral comfort, and minimize treatment interruptions.
Official title: Effectiveness of Different Mouthwash Temperatures on Oral Mucositis Pain and Patient Comfort During Radiotherapy for Head and Neck Cancer: A Randomized Controlled Trial
Key Details
Gender
All
Age Range
20 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2026-01-01
Completion Date
2027-03-31
Last Updated
2025-11-26
Healthy Volunteers
No
Conditions
Interventions
Water Rinse at Different Temperatures
rinse their mouth with cold water at approximately 15-20°C
Locations (1)
Chung Shan Medical University
Taichung, Taiwan (r.o.c.), Taiwan