Clinical Research Directory

Inclusion Criteria: * Person with a clear Multiple Sclerosis diagnosis according to the 2017 revision of the McDonald criteria since at least 3 months. * Person with an Expanded Disability Status Scale (EDSS) score ≥ 4 and ≤ 6 * Person with stable walking ability for at least two weeks prior to the inclusion visit (variation at the MSWS-12 questionnaire \< 8/100 points) * Person not treated with fampridine due to contra-indication or adverse events or not respondent or no longer respondent or reluctant to taking drugs * Person with spasticity at the lower limb(s), attested by a Modified Ashworth Scale ≥ 1+ of at least one of the following muscle groups: quadriceps, hamstrings, triceps surae, tibialis anterior * Person who never tried EXOPULSE SUIT Exclusion Criteria: * Person under 18 years old * Person having a contraindication to using EXOPULSE SUIT * Person using an electronic life-support equipment, e.g. pacemakers or hight-frequency surgical equipment and person using an ECG equipment * Person affected by other somatic or neuropsychiatric diagnoses (e.g., arrhythmias, uncontrolled epilepsy, diseases causing osteoarticular and muscular pain). * Person with relapses over the last 3 months before the inclusion * Person who had a modification of his/her medical treatments of the multiple sclerosis or related to motor performance over the last 3 months before the inclusion * Person who had a new medical treatment of the multiple sclerosis or related to motor performance over the last 3 months before the inclusion * Person who had an injection of botulinum toxin in at least one of the main muscle groups of the lower limbs over the last 4 months before the inclusion * Person planning to use a new medical device during the study (ex: ankle-foot orthosis…) * Person undergoing or planning to undergo an intensive rehabilitation phase * Person that is part of another study * Person who cannot be fitted with EXOPULSE SUIT due to inexistent Suitable size of the Suit (eg: BMI\>35; user height \< 100 cm or \> 205cm) * Person who does not have a smartphone or who cannot or does not want to use his/her smartphone for operating the EXOPULSE App * Person not available to undergo all medical visits during the study * Person unable to understand verbal and written instructions in french * Pregnant person * Persons under juridical protection * Prisoners