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GEL & MEDication Dysphagia
Sponsor: Heinrich-Heine University, Duesseldorf
Summary
This research project examines the prevalence of medication-related dysphagia in patients with dysphagia-associated diseases. Its primary aim is to assess how frequently swallowing difficulties occur during medication intake and to evaluate the impact of different consistencies-such as semi-solid formulations and commercial swallowing gels-on the swallowing process. Flexible endoscopic evaluation of swallowing serves as the diagnostic gold standard to determine whether alternative administration forms can facilitate safer swallowing. The findings are intended to support the optimization of medication intake and the prevention of complications in patients with dysphagia.
Official title: Influence of Swallow Gel and Semi-solid Consistency on Medication Dysphagia: A Multicenter Observational Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
500
Start Date
2025-09-15
Completion Date
2027-09-15
Last Updated
2025-11-28
Healthy Volunteers
Yes
Interventions
medication swallowing
Three swallow trials will be conducted in randomized order for each of the following conditions: 1. Placebo medication with methylene-blue-dyed water. 2. Placebo medication with a semi-solid vehicle. 3. Placebo medication with the swallowing gel GLOUP®.
Locations (3)
University Hospital Düsseldorf
Düsseldorf, North Rhine-Westphalia, Germany
University Hospital Münster
Münster, North Rhine-Westphalia, Germany
Hospital Osnabrücl
Onsabrück, Germany