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Effect of Itopride on Semaglutide Gastroparesis
Sponsor: Ain Shams University
Summary
Semaglutide delays gastric emptying and increases the risk of aspiration with anesthesia; So, the addition of prokinetics as Itopride, could enhance gastric emptying and hasten surgery. The investigator will evaluate the effect of Itopride on Semaglutide-induced gastroparesis and residual gastric contents after 8 hours of fasting by gastric ultrasound before anesthesia.
Official title: Does Itopride Improve Semaglutide Induced Gastroparesis Ultrasound Before Anesthesia? Randomized Controlled Trial
Key Details
Gender
FEMALE
Age Range
40 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2025-12
Completion Date
2026-04
Last Updated
2025-11-28
Healthy Volunteers
No
Interventions
Itopride HCI 50 mg
Daily oral 50mg Itopride tablet TID, 1 hour before meals for 7 days
Placebo
Daily placebo tablet TID, 1 hour before meals for 7 days
Locations (1)
faculty of medicine, Ain Shams University
Cairo, Cairo Governorate, Egypt