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RECRUITING
NCT07255469

Metabolic Fluid Responsiveness in Children

Sponsor: University Hospital, Bordeaux

View on ClinicalTrials.gov

Summary

The investigators aim to validate markers of metabolic fluid-responsiveness in children with acute circulatory failure following cardiac surgery. This would allow physicians to identify which patient could benefit the most from fluid expansion, thus avoiding useless and potentially dangerous fluid expansions that could lead to fluid overload. To this end, The investigators will evaluate the diagnostic accuracy of the ratio of central venous to arterial carbon dioxide tension (Pv-aCO2) to arteriovenous oxygen content (CavO2), a simple biological marker of anaerobic metabolism, for the diagnosis of metabolic fluid responsiveness defined as a significant increase in oxygen consumption (VO2) after fluid expansion.

Official title: Parameters Associated With Metabolic Response to Volume Expansion in Children Post-operative of Cardiac Surgery

Key Details

Gender

All

Age Range

0 Days - 15 Years

Study Type

OBSERVATIONAL

Enrollment

110

Start Date

2025-03-21

Completion Date

2027-04-18

Last Updated

2025-12-01

Healthy Volunteers

No

Locations (8)

Hôpital Louis Pradel - Hospices Civils de Lyon

Bron, France, France

Hôpital Jeanne de Flandre - CHU de Lille

Lille, France, France

Hôpital de la Timone - Assistance Publique - Hôpitaux de Marseille

Marseille, France, France

Hôpital mère-enfant - CHU de Nantes

Nantes, France, France

Hôpital Necker-Enfants Malades - Assistance Publique - Hôpitaux de Paris

Paris, France, France

Hôpital Cardiologique Haut Lévêque - CHU de Bordeaux

Pessac, France, France

Hôpital des enfants - CHU de Toulouse

Toulouse, France, France

Hôpital Felix Guyon - CHU de la Réunion

Saint-Denis, La Réunion, France