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RECRUITING
NCT07255859
NA

AVIGA3 (Cohort 2.0)

Sponsor: Tan Tock Seng Hospital

View on ClinicalTrials.gov

Summary

Age-Macular Degeneration (AMD) is a common eye condition and a leading cause of vision loss among people age 50 and older. It causes damage to the macula, a small area near the centre of the retina needed for sharp, central vision. It is estimated that the prevalence of early and late AMD in Asian populations aged 40 to 79 were 6.8% and 0.56% respectively. Prevalence in white populations estimated from large population studies were 8.8% and 0.59% respectively. With the aging population and people living longer, these numbers will only increase. Hence, this study aims to develop a system to evaluate the AVIGA system through remote monitoring for disease recurrence of wet aged-related macular degeneration using eye gaze tracking.

Official title: AVIGA3: Using an 'Automated Vision Assessment and Impairment Detection Through Gaze Analysis' Through a Longitudinal, Open-labelled, Randomized Clinical Trial to Monitor Recurrence of Aged-related Macular Degeneration in a Home-based Setting (Cohort 2.0).

Key Details

Gender

All

Age Range

50 Years - 99 Years

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2025-06-16

Completion Date

2027-12-31

Last Updated

2026-06-24

Healthy Volunteers

No

Conditions

Interventions

DIAGNOSTIC_TEST

Amsler Grid

The Amsler grid is a tool used to monitor the macula, the central part of the retina, for changes in vision that can be indicative of various eye conditions, particularly age-related macular degeneration (AMD). It helps detect and monitor metamorphopsia (distorted vision) or scotoma (blind spots) in the central visual field.

DEVICE

AVIGA

The AVIGA system tracks these eye movements with generated patterns on the screen, a visual assessment of affected and unaffected eyes is achieved at home on any tablet or laptop computer. AVIGA is a home-based gaze-tracking system for hyperacuity monitoring of high-risk eyes with diagnosed wet-AMD.

Locations (1)

Tan Tock Seng Hospital

Singapore, Singapore