Clinical Research Directory

Metagenomic Next-Generation Sequencing for the Diagnosis of Fracture-related Infection

Sponsor: Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer

Summary

The value of next-generation sequencing (NGS) using Nanopore technology has been demonstrated in the case of diabetic patients' wounds or in prosthetic joint infections. The aim of this study is to demonstrate its relevance as a new diagnostic approach for fracture-related infections (FRI). Bone samples from patient with FRI will be submitted to shotgun metagenomic Next-generation sequencing using Oxford Nanopore Technology (ONT) in order to establish its diagnostic value in this context in comparison with the reference method.

Official title: Contribution of Metagenomic Sequencing Using Nanopore Technology to the Management of Post-traumatic Bone and Joint Infections

Key Details

Conditions

Interventions

Locations (2)