Clinical Research Directory

PATIENTS Inclusion Criteria * Age ≥ 18 years * Patient who has undergone excision of a cutaneous, mucocutaneous, or vestibular nasal cancer with surgical reconstruction using a flap or prosthetic rehabilitation, performed more than 4 months ago, with stable results, and less than 3 years ago * Patient informed of the study and not opposed to participation Exclusion Criteria * Patient under anticoagulant or antiplatelet therapy Non-French-speaking patient * Patient under legal protection (e.g., guardianship, legal safeguard) or with limited legal capacity * Patient unlikely to cooperate with the study and/or poor anticipated compliance as judged by the investigator (including psychiatric disorders other than depressive disorder or cognitive impairment) * Pregnant or breastfeeding woman CONTROL Inclusion Criteria * Age ≥ 65 years * Subject informed and not opposed to participating in the study * Subject who has never undergone facial trauma or surgery, and without major comorbidity, defined as follows: * No heart failure (moderate or severe heart failure, history of heart attack within the last 6 months); * No severe chronic respiratory disease (no stage III-IV COPD, no prolonged oxygen therapy); * No uncontrolled diabetes or associated severe complications; * No active immunosuppressive diseases or high-dose immunosuppressive treatment; * No unstable or severe facial dermatological conditions; * No comorbidities seriously affecting quality of life or respiratory function (at the investigator's discretion). Exclusion Criteria * Non-English speaking subject * Subject under guardianship or legal protection, legally incompetent or with limited legal capacity * Subject unlikely to cooperate in the study and/or anticipated low cooperation by the investigator (particularly those with psychiatric disorders other than depression or cognitive disorders) * Pregnant or breastfeeding women