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Compare Stoma Reversal Wound Outcomes Between NPWT and Secondary Intention Healing
Sponsor: Maryam Arbab
Summary
This was a single-center, parallel-group randomized controlled trial conducted in 2025 at the General Surgery Ward of the Sindh Institute of Urology and Transplantation (SIUT), Karachi. The study compared negative pressure wound therapy (NPWT) with healing by secondary intention (SIH) for patients undergoing stoma reversal surgery.
Official title: Negative Pressure Wound Therapy Versus Secondary Intention Healing in Stoma Reversal: A Randomized Controlled Trial Evaluating Surgical Site Infection and Wound Outcomes
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
72
Start Date
2025-02-24
Completion Date
2025-08-30
Last Updated
2026-09-23
Healthy Volunteers
No
Interventions
Negative Pressure Wound Therapy
In the NPWT (negative pressure wound therapy) group, after the procedure, the skin was left open and covered with four sterile gauze layers. An 18 Fr Nelaton catheter was placed directly over the wound and sealed with transparent, waterproof adhesive to create a vacuum. Continuous negative pressure was applied at 15 mmHg. Dressings were evaluated for SSI on postoperative days 2 and 4 using the ASEPSIS score; if no infection was present, NPWT dressing was reapplied. On postoperative day 6, final wound assessment was conducted and further management was carried out as per departmental protocol.
Locations (1)
Sindh Institute of Urology and Transplantation
Karachi, Sindh, Pakistan