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Generation of Endometrial Carcinoma Organoids
Sponsor: Regina Elena Cancer Institute
Summary
A prospective pilot genetic study to evaluate the feasibility of generating organoids from endometrial tumor tissue collected during surgery, performed according to standard clinical practice. Samples will be collected from collaborating extramural facilities, with the aim of analyzing the impact of transport on tissue viability and the success of organoid culture. This study is for exploratory purposes only, without altering the diagnostic and therapeutic pathways of the participants.
Official title: Feasibility Study of the Generation of Endometrial Carcinoma Organoids From Tumor Samples Transferred From Extramural Facilities
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
20
Start Date
2025-03-23
Completion Date
2028-09-23
Last Updated
2025-12-02
Healthy Volunteers
No
Conditions
Interventions
Generation of organoids from endometrial tumor tissue collected during surgery, performed according to standard clinical practice
Creation of endometrial carcinoma organoids from tumor tissue from extramural structures, verifying the feasibility of organoid generation. Evaluate the impact of sample transport and storage conditions on the success of the process, considering the challenges associated with preserving tissue integrity.
Locations (1)
IRCCS National Cancer Institute "Regina Elena"
Roma, Roma, Italy