Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
RECRUITING
NCT07258849
PHASE1

A Study of LY4213663 in Healthy Participants and Participants With Rheumatoid Arthritis

Sponsor: Eli Lilly and Company

View on ClinicalTrials.gov

Summary

The purpose of this study is to evaluate how well LY4213663 is tolerated and what side effects may occur in healthy participants and participants with rheumatoid arthritis (RA). The study drug will be administered either subcutaneously (SC) (under the skin) or intravenously (IV) (into a vein in the arm). Blood tests will be performed to investigate how the body processes the study drug and how the study drug affects the body. The study will last approximately 33 weeks excluding screening.

Official title: A Phase 1, Multicenter, Randomized, Placebo-Controlled, Investigator- and Participant-Blinded, Single- and Multiple-Ascending Dose Study to Evaluate Safety, Tolerability, and Pharmacokinetics of LY4213663 in Healthy Participants, and Two Open-Label, Multiple-Dose Evaluations of LY4213663 in Patients With Rheumatoid Arthritis.

Key Details

Gender

All

Age Range

18 Years - 75 Years

Study Type

INTERVENTIONAL

Enrollment

134

Start Date

2025-12-02

Completion Date

2028-03

Last Updated

2026-01-20

Healthy Volunteers

Yes

Interventions

DRUG

LY4213663

Administered SC

DRUG

LY4213663

Administered IV

DRUG

Placebo

Administered SC

DRUG

Placebo

Administered IV

Locations (9)

Pinnacle Research Group, LLC

Anniston, Alabama, United States

Arizona Research Center

Phoenix, Arizona, United States

Clinical Research of West Florida, Inc. (Clearwater)

Clearwater, Florida, United States

GNP Research at Mark Jaffe, MD

Cooper City, Florida, United States

Fortrea Clinical Research Unit

Daytona Beach, Florida, United States

AGA Clinical Trials

Hialeah, Florida, United States

Advanced Pharma CR, LLC

Miami, Florida, United States

Floridian Clinical Research

Miami Lakes, Florida, United States

Oasis Clinical Research

Las Vegas, Nevada, United States