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Hypertension in Children and Young People at Risk of Autosomal Dominant Polycystic Kidney Disease
Sponsor: King's College London
Summary
The goal of this project is to measure the prevalence of Autosomal Dominant Polycystic Kidney Disease (ADPKD) and hypertension in the general population of children and young people at risk of ADPKD, using magnetic resonance imaging (MRI) for rapid diagnosis alongside genetic testing. The main question it aims to answer is: What is the prevalence of hypertension in a population sample of adolescents with ADPKD? Participants will have the following measurements performed: * Height and weight. * Blood pressure. * Non-invasive measurement of arterial stiffness. * Cardiac and renal MRI. * Blood sample. * Genetic testing.
Official title: Family Study of Early Hypertension in Children and Young People at Risk of Autosomal Dominant Polycystic Kidney Disease
Key Details
Gender
All
Age Range
12 Years - 17 Years
Study Type
OBSERVATIONAL
Enrollment
200
Start Date
2025-08-15
Completion Date
2028-03
Last Updated
2025-12-02
Healthy Volunteers
No
Locations (1)
Evelina London Children's Hospital
London, United Kingdom