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RECRUITING
NCT07260071

Hypertension in Children and Young People at Risk of Autosomal Dominant Polycystic Kidney Disease

Sponsor: King's College London

View on ClinicalTrials.gov

Summary

The goal of this project is to measure the prevalence of Autosomal Dominant Polycystic Kidney Disease (ADPKD) and hypertension in the general population of children and young people at risk of ADPKD, using magnetic resonance imaging (MRI) for rapid diagnosis alongside genetic testing. The main question it aims to answer is: What is the prevalence of hypertension in a population sample of adolescents with ADPKD? Participants will have the following measurements performed: * Height and weight. * Blood pressure. * Non-invasive measurement of arterial stiffness. * Cardiac and renal MRI. * Blood sample. * Genetic testing.

Official title: Family Study of Early Hypertension in Children and Young People at Risk of Autosomal Dominant Polycystic Kidney Disease

Key Details

Gender

All

Age Range

12 Years - 17 Years

Study Type

OBSERVATIONAL

Enrollment

200

Start Date

2025-08-15

Completion Date

2028-03

Last Updated

2025-12-02

Healthy Volunteers

No

Locations (1)

Evelina London Children's Hospital

London, United Kingdom