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Recovery Rate From Category II to Category I EFM Tracings in Pregnant Women Receiving Bolus vs Continuous Intravenous Fluid Administration
Sponsor: Queen Savang Vadhana Memorial Hospital, Thailand
Summary
This randomized trial compared a normal saline bolus regimen with continuous normal saline infusion. The participants were low-risk pregnant women at term with Category II fetal heart rate tracings. Both groups were prescribed 1,000 mL of normal saline through the same volumetric infusion pump. The bolus group received 500 mL at 1,000 mL/h during the first 30 minutes, followed by 150 mL/h. The continuous group received 150 mL/h throughout. The primary outcome was first recovery from Category II to Category I within 30 minutes. Both groups also received standard intrauterine resuscitation. Fetal heart rate tracings were assessed at 30, 60, and 120 minutes.
Key Details
Gender
FEMALE
Age Range
20 Years - 35 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2025-12-10
Completion Date
2026-03-31
Last Updated
2026-08-17
Healthy Volunteers
No
Conditions
Interventions
Normal saline bolus infusion
Participants were prescribed 1,000 mL of normal saline through a 21-gauge cannula and the same volumetric infusion pump. The first 500 mL was administered at 1,000 mL/h during the first 30 minutes. The remaining 500 mL was then administered at 150 mL/h. The intervention continued until the attending declared Category I recovery or until 120 minutes.
Continuous normal saline infusion
Participants were prescribed 1,000 mL of normal saline through a 21-gauge cannula and the same volumetric infusion pump. Normal saline was administered continuously at 150 mL/h throughout. The intervention continued until the attending declared Category I recovery or until 120 minutes.
Locations (1)
Queen Savang Vadhana Memorial Hospital
Si Racha, Changwat Chon Buri, Thailand