Clinical Research Directory

Inclusion Criteria: 1. Able to understand and comply with the protocol requirements, participate and sign the informed consent form (ICF) voluntarily; 2. At least 18 years of age at the time of signing the ICF, with no gender restrictions; 3. Meet the 1984 modified New York criteria for ankylosing spondylitis (AS); 4. Have inadequate response to non-steroidal anti-inflammatory drugs (NSAIDs) or have contraindications/intolerance to NSAIDs treatment; 5. Willing to practice contraception and have no plans for pregnancy, sperm donation, or egg donation from the screening period until at least 6 months after the last dose. Exclusion Criteria: 1. Patients with other uncontrolled active inflammatory diseases. 2. Clinical laboratory tests and other tests that reveal abnormalities with clinical significance 3. Patients who have active Hepatitis B, Hepatitis C or HIV infections as determined by positive results at Screening. 4. History of cancer. 5. Known or suspected history of immunosuppression.