PRIOR Study (Pre-eclampsia Risk In Oocyte Recipients)

RECRUITING

NCT07263490

Sponsor: Copenhagen University Hospital, Hvidovre

Summary

The aim of this prospective observational cohort study is to investigate the pathophysiological mechanisms behind and risk of pre-eclampsia in women pregnant after fertility treatment with oocyte donation. The participants are included in of of two cohorts. One includes women pregnant after oocyte donation whereas the other includes women pregnant after IVF treatment with autologous oocytes. Participants will be followed throughout pregnancy with blood samples, blood pressure, clinical controls and ultrasound examinations. Clinical outcomes will be registered post-partum.

Official title: PRIOR Study (Pre-eclampsia Risk In Oocyte Recipients) - Investigating Matching, Biomarkers and Outcomes.

Key Details

Gender

FEMALE

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

462

Start Date

2024-10-21

Completion Date

2028-06-01

Last Updated

2025-12-04

Healthy Volunteers

No

Conditions

Pre-eclampsia Oocyte Donation Pre-Eclampsia; Complicating Pregnancy Pre-Eclampsia; Mild Pre-Eclampsia, Severe Pre-eclampsia or Eclampsia With Pre-existing Hypertension ART Neonatal Morbidity Neonatal Mortality Placental Abruption Gestational Diabetes Preterm Labor Post-partum Hemorrhage (PPH)Intrauterine Growth Restriction (IUGR)Hypertensive Disorders of Pregnancy

Locations (6)

Copenhagen Fertility Center

Copenhagen, Denmark

Trianglen Fertility Clinic

Hellerup, Denmark

Fertility Clinic, Herlev / Gentofte Hospital

Herlev, Denmark

Sellmer Klinik

København S, Denmark

Fertility Clinic, Rigshospitalet

København Ø, Denmark

Aleris Fertility

Søborg, Denmark

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