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Exercise During Pregnancy: Effects on the Maternal-Fetal Unit
Sponsor: Universidad Pública de Navarra
Summary
Metabolic alterations during pregnancy have been associated with adverse maternal-fetal outcomes, including low birth weight and pregnancy complications. Maternal endothelial dysfunction, oxidative stress, insulin resistance, and placental mitochondrial dysfunction are thought to contribute to fetal metabolic disturbances. Lifestyle changes, such as structured exercise during pregnancy, may modulate maternal and placental factors. This randomized controlled trial will evaluate the effects of a multicomponent exercise program during the second and third trimester on maternal functional capacity, vascular health, anthropometry, metabolic biomarkers, placental function, and newborn health outcomes.
Official title: Benefits of Exercise for the Maternal-Fetal Unit During Pregnancy
Key Details
Gender
FEMALE
Age Range
18 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
64
Start Date
2025-09-01
Completion Date
2027-12-20
Last Updated
2025-12-04
Healthy Volunteers
Yes
Conditions
Interventions
Intervention
Exercise
Locations (1)
Navarrabiomed, Hospital Universitario de Navarra (HUN) and Universidad Pública de Navarra (UPNA)
Pamplona, Navarre, Spain