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ENROLLING BY INVITATION
NCT07268599

Moderate-to-Severe Dry Eye Disease Relief Using Acoltremon

Sponsor: Colvard Kandavel Eye Center

View on ClinicalTrials.gov

Summary

To evaluate the impact of Acoltremon 0.003% on subjective dry eye symptoms using validated patient-reported outcome measures: Eye Dryness Score Visual Analog Scale (EDS-VAS). The primary aim is to characterize the rapidity of symptomatic relief in moderate to severe dry eye disease (DED), with attention to short-term therapy.

Official title: Acoltremon Symptom Tracking and Relief Assessment in Moderate-to-Severe Dry Eye Disease

Key Details

Gender

All

Age Range

18 Years - 60 Years

Study Type

OBSERVATIONAL

Enrollment

50

Start Date

2025-11-24

Completion Date

2026-10

Last Updated

2025-12-08

Healthy Volunteers

Not specified

Interventions

DRUG

Acoltremon

Patients will administer Acoltremon 0.003% as per labeled directions. Assessments with the Ocular Surface Disease Index (OSDI) will occur at Baseline, treatment at 14 days, and treatment at 28 days. Secondary endpoints include change from baseline rating scale 1-5 in severity of various symptoms of dry eye: Blurriness, eye irritation/Discomfort, Burning/Stinging, Photophobia/Pain, Sandy/gritty/Foreign Body Sensation, Fatigue/Tired Eyes).

Locations (1)

Colvard-Kandavel Eye Center

Encino, California, United States