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Investigation of Pathogenic Gut Microbiota Patterns in Anxiety, Depression and Panic Disorders
Sponsor: University of Toronto
Summary
This study aims to investigate the etiology of anxiety, depression, and panic disorders, providing new evidence and insights into the root causes and effective treatments, potentially offering a novel approach to achieving complete recovery.
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
OBSERVATIONAL
Enrollment
500
Start Date
2025-12-10
Completion Date
2026-01-10
Last Updated
2025-12-08
Healthy Volunteers
Yes
Interventions
H pylori stool test
Participants will provide a stool sample for noninvasive testing to detect the presence of Helicobacter pylori bacteria. The test will be performed using a validated laboratory assay that identifies H. pylori antigens in stool. Results will be used to assess potential associations between H. pylori infection, gut microbiome composition, and symptoms of anxiety or depression. The test is diagnostic only and does not involve administration of any drug or treatment.
Bacterial stool analysis
Participants will provide stool samples for microbiome sequencing using a validated laboratory assay. The analysis will characterize bacterial taxa within the gut microbiome and identify potential pathogenic species. Sequencing results will be correlated with psychological assessments and clinical measures to investigate relationships between gut microbial composition and symptoms of anxiety, depression, and panic disorder.
Locations (1)
MedBliss Research Network
Mississauga, Ontario, Canada