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Validate the Effect of Calcium Oral Spray on Early Childhood Caries
Sponsor: Tri-Service General Hospital (TSGH)
Summary
This exploratory randomized clinical trial aimed to evaluate the effects of calcium-containing oral sprays on the primary clinical outcome, fluorescence-detectable plaque-associated area measured by quantitative light-induced fluorescence (QLF). Fifteen children were randomly assigned to placebo, Formula 1 (0.3% calcium lactate), or Formula 2 (0.3% calcium lactate plus 225 ppm fluoride) oral sprays for two months. Secondary outcomes included salivary calcium concentration and exploratory plaque microbiome analysis.
Official title: Validate the Effect of T-spray on ECC in Clinical Trials
Key Details
Gender
All
Age Range
3 Years - 15 Years
Study Type
OBSERVATIONAL
Enrollment
15
Start Date
2023-06-11
Completion Date
2025-11-11
Last Updated
2026-07-14
Healthy Volunteers
No
Locations (1)
Tri-Service General Hospital
Taipei, Taiwan, Taiwan