Clinical Research Directory

Inclusion Criteria Each subject must meet all of the following criteria and be confirmed with electronic medical records: 1. Confirmed HIV diagnosis and currently a patient in the WashU Infectious Disease Clinic 2. Age 25-65 years 3. All people with HIV must be currently receiving stable antiretroviral therapy 4. People with HIV with insomnia must report Insomnia Severity Index \>/= 15 at initial screening and meet DSM-5 diagnostic criteria for insomnia including sleep difficulty that occurs at least 3 times per week and has been a problem for at least 3 consecutive months 5. People with HIV must also report the presence of chronic pain on the Brief Chronic Pain Screening Questionnaire and rate their chronic pain as \>/= 3 on a 0-10 scale of intensity. Exclusion Criteria Subjects will not be enrolled if any of the following criteria exist and confirmed with electronic medical records: 1. History of stroke in past 12 months 2. Active cancer with treatment 3. Heart disease 4. Uncontrolled hypertension 5. Epilepsy 6. Active pregnancy 7. Reynaud's disease 8. Traumatic injury or surgical procedure within the last 12 months 9. Acute infection as suggested by thermometry temperature \>100.4 10. Serious psychiatric disorder (bipolar disorder, psychotic disorder) 11. Active suicidal ideation 12. Evidence for severe obstructive sleep apnea (AHI \>30/hr) according to Home Sleep Monitoring or presence of another sleep disorder other than insomnia (i.e., not insomnia) as indicated by SCISD-R