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ACTIVE NOT RECRUITING
NCT07270510
PHASE4

The Effect of Collagen In Tooth Extraction Procedures

Sponsor: Altinbas University

View on ClinicalTrials.gov

Summary

This study is aimed at assessing the effect of an animal-derived collagen matrix on bone and soft tissues in the human teeth. Single-rooted teeth that are beyond restoration and in need of extraction will be included in the study. Patients will be divided into two comparable groups in a randomized manner. The first group will proceed with tooth extraction only, which will be left for spontaneous healing. The second (test) group will receive an additional collagen matrix graft after the extraction, which will be sutured to the tooth socket. Sutures will be removed 1 week after surgery. Both groups will undergo CBCT imaging on the day of surgery and at the 3-month follow-up. Differences in bone measurements like height and width will be recorded as well as soft tissue measurements like thickness and width. Data acquired from two groups will be compared against each other to specify the protective effect of the applied collagen matrix graft.

Official title: Clinical and Volumetric Evaluation of Collagen Matrix Efficacy in Alveolar Socket Preservation, Randomized Clincal Trial

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

24

Start Date

2025-07-01

Completion Date

2026-02-20

Last Updated

2025-12-08

Healthy Volunteers

Yes

Interventions

DEVICE

Collagen Matrix soft tissue graft

Circular 8 mm diameter collagen matrix grafts were sutured to seal extraction sockets in the participants. The sutures were removed 1 week after the intervention.

Locations (1)

Altinbas University

Istanbul, Istanbul, Turkey (Türkiye)