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A Research Study to See if Two Different Formulations of Oral Semaglutide Are Equally Safe and Effective in Reducing the Blood Sugar Level in Japanese People With Type 2 Diabetes
Sponsor: Novo Nordisk A/S
Summary
The purpose of the study is to find out if the new tablet formulation oral semaglutide D is equally safe and effective as the approved oral semaglutide for treating Japanese people with type 2 diabetes. Participants will receive either oral semaglutide D (the treatment being tested) or oral semaglutide (the comparator); which treatment a participant gets is decided by chance. Oral semaglutide is an approved tablet (a treatment used as a comparator), while oral semaglutide D is described as the new tablet formulation being tested in this study. The study will last approximately 27 weeks.
Official title: A Study Investigating Clinical Comparability of Two Formulations of Oral Semaglutide in Japanese Participants With Type 2 Diabetes
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
264
Start Date
2025-12-01
Completion Date
2026-08-03
Last Updated
2026-03-31
Healthy Volunteers
No
Conditions
Interventions
Oral semaglutide
Semaglutide will be administered orally once daily.
Locations (15)
Seino Internal Medicine Clinic_Internal medicine
Koriyama-shi, Fukushima, Fukushima, Japan, Japan
Hayashi Diabetes Clinic_Internal Medicine and Diabetes Medicine
Chigasaki-shi, Kanagawa, Japan, Japan
Jinnouchi Hospital_Internal Medicine
Kumamoto, Kumamoto, Japan, Japan
Heiwadai Hospital_Internal Medicine
Miyazaki, Miyazaki, Japan
TOSAKI Clinic for Diabetes and Endocrinology_Diabetes and Endocrinology
Aichi, Japan
Tokuyama clinic_Diabetic internal medicine
Chiba, Japan
Futata Tetsuhiro Clinic Meinohama_Internal medicine
Fukuoka-shi, Fukuoka, Japan
Oodouri Diabetes, Internal medicine Clinic_Internal Medicine, Diabetes Internal Medicine
Hokkaido, Japan
Naka Kinen Clinic_Internal medicine
Ibaraki, Japan
Yokohama Minoru Clinic_Internal medicine
Kanagawa, Japan
Shonan Takai Clinic_Internal Medicine
Kanagawa, Japan
Soka Sugiura Internal Medicine Clinic
Soka-shi, Saitama, Japan
Oyama East Clinic_Internal Medicine
Tochigi, Japan
Tokyo-Eki Center-building Clinic_Internal Medicine
Tokyo, Japan
Kato Clinic of Internal Medicine_Internal Medicine
Tokyo, Japan