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NOT YET RECRUITING
NCT07272109
PHASE3

Active Anti-diabetic Treatment Plus Chemotherapy for Pancreatic Cancer Related Diabetes

Sponsor: Fudan University

View on ClinicalTrials.gov

Summary

The purpose of this study is to evaluate the efficacy of anti-diabetic treatment on improving the overall survival for metastatic pancreatic cancer patients complicated by diabetes receiving gemcitabine and nab-paclitaxel chemotherapy.

Official title: Active Anti-diabetic Treatment Plus Chemotherapy for Metastatic Pancreatic Cancer Related Diabetes Mellitus (Type 3c)

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

210

Start Date

2026-01-01

Completion Date

2028-12-30

Last Updated

2025-12-15

Healthy Volunteers

No

Interventions

DRUG

Nab-paclitaxel

120 mg per square meter of body-surface area on days 1, 8, and 15 every 4 weeks

DRUG

Gemcitabine (1000 mg/m2)

(1000 mg per square meter) on days 1, 8, and 15 every 4 weeks

OTHER

Anti-Diabetics

Metformin, insulin or other anti-diabetic treatments

OTHER

Active treatment and monitoring

Attend follow-ups at designated endocrinology clinics, with proactive inquiry about hypoglycemic measures and medication implementation.

Locations (1)

Shanghai Cancer Center

Shanghai, China