Clinical Research Directory

Inclusion criteria: * Age of 40-80 years; * a history of ischemic stroke resulting in unilateral limb impairment 6-60 months prior to consent to participate in the pilot trial; * a stable medical condition; * a subjective feeling of fatigue, defined as a period of apparent fatigue, decreased energy, increased need for rest, or fatigue out of proportion to physical activity for at least 2 weeks during the past month; * ability to communicate with the investigators and lack of significant cognitive deficits; * able to walk for 10 meters with or without a walking aid. Exclusion criteria: * An FSS score of \< 4 (20); * other neurological conditions; * other musculoskeletal comorbidities that would prevent safe participation in exercises; * a medical diagnosis of significant cardiovascular, pulmonary, or metabolic disease(s); * signs or symptoms indicative of significant cardiovascular, pulmonary, or metabolic disease(s) during the previous 3 months; * severe lower limb spasticity (Ashworth Scale score ≥ 3); * Botulinum toxin use in the affected lower limb within the past six months; * current or previous use of drugs intended to resolve post-stroke fatigue; * active engagement in other stroke rehabilitation trials.