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Periodontal Health and Sodium Bicarbonate Toothpaste
Sponsor: University of Plymouth
Summary
The goal of this clinical trial is to determine whether sodium bicarbonate fluoride toothpaste can help maintain periodontal health in adults who have undergone non-surgical periodontal treatment. The main question it aims to answer is: Does daily use of toothpaste affect the following outcomes: clinical oral health (plaque scores, gingival bleeding scores and periodontal pocket depths), salivary biochemical markers and the oral microbiome. Outcomes measures will be recorded at 0,3, and 6 months, during which time participants will receive either the treatment or placebo toothpaste and undergo oral hygiene instruction and PMPR over 6 months.
Official title: Maintenance of Periodontal Health With Daily Use of Sodium Bicarbonate Toothpaste
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2024-12-04
Completion Date
2027-01-30
Last Updated
2025-12-22
Healthy Volunteers
No
Conditions
Interventions
no treatment received
Baseline; 0 months (no periodontal treatment)
Periodontal treatment and OHI
3 months periodontal treatment \& OHI
Periodontal treatment and OHI
6 months periodontal treatment \& OHI
Locations (1)
Derriford Dental Education Facility
Plymouth, United Kingdom