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RECRUITING
NCT07274189
NA

Periodontal Health and Sodium Bicarbonate Toothpaste

Sponsor: University of Plymouth

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to determine whether sodium bicarbonate fluoride toothpaste can help maintain periodontal health in adults who have undergone non-surgical periodontal treatment. The main question it aims to answer is: Does daily use of toothpaste affect the following outcomes: clinical oral health (plaque scores, gingival bleeding scores and periodontal pocket depths), salivary biochemical markers and the oral microbiome. Outcomes measures will be recorded at 0,3, and 6 months, during which time participants will receive either the treatment or placebo toothpaste and undergo oral hygiene instruction and PMPR over 6 months.

Official title: Maintenance of Periodontal Health With Daily Use of Sodium Bicarbonate Toothpaste

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2024-12-04

Completion Date

2027-01-30

Last Updated

2025-12-22

Healthy Volunteers

No

Interventions

PROCEDURE

no treatment received

Baseline; 0 months (no periodontal treatment)

PROCEDURE

Periodontal treatment and OHI

3 months periodontal treatment \& OHI

PROCEDURE

Periodontal treatment and OHI

6 months periodontal treatment \& OHI

Locations (1)

Derriford Dental Education Facility

Plymouth, United Kingdom