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Emulation of the MONALEESA-2 Trial Using Specialty Oncology Electronic Health Records Databases
Sponsor: Shirley Vichy Wang
Summary
Investigators are building an empirical evidence base for real world data through large-scale emulation of randomized controlled trials. The investigators' goal is to understand for what types of clinical questions real world data analyses can be conducted with confidence and how to implement such studies.
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
2495
Start Date
2025-09-07
Completion Date
2026-01-01
Last Updated
2026-05-12
Healthy Volunteers
No
Conditions
Interventions
Initiation of ribociclib
Initiation of ribociclib plus letrozole described in electronic health records is used as the exposure
Initiation of letrozole
Initiation of letrozole described in electronic health records is used as the reference
Locations (1)
Brigham and Women's Hospital
Boston, Massachusetts, United States