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Neural Mechanisms of Fatigue in Post-Acute Sequela of SARS-CoV-2
Sponsor: Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Summary
This proposal aims to understand the neurobiological mechanisms of fatigue in individuals with Post-Acute Sequelae of SARS-CoV-2 Infection (PASC). This knowledge will eventually provide candidate mechanisms to target with pharmacological intervention and inform rehabilitative care for those individuals suffering from symptoms of fatigue in PASC.
Official title: Motivated Decision-Making and Performance
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2025-07-16
Completion Date
2029-12-31
Last Updated
2025-12-12
Healthy Volunteers
Yes
Interventions
Physical Fatigue
Participants will perform a physically demanding task (grip force exertion task) repeatedly to induce physical fatigue.
Locations (1)
Kennedy Krieger Institute
Baltimore, Maryland, United States