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Combined Brain Stimulation and Methylphenidate Treatment for Apathy in Dementia
Sponsor: Sunnybrook Health Sciences Centre
Summary
This study evaluates whether the combined treatment of methylphenidate and non-invasive brain stimulation, called intermittent theta burst stimulation, can effectively treat apathy in individuals with Alzheimer's disease or mixed AD/vascular dementia
Official title: Methylphenidate Primed iTBS for Apathy in Neurocognitive Disorders
Key Details
Gender
All
Age Range
Any - Any
Study Type
INTERVENTIONAL
Enrollment
12
Start Date
2026-01
Completion Date
2027-10-01
Last Updated
2025-12-12
Healthy Volunteers
No
Conditions
Interventions
intermittent theta burst stimulation (iTBS)
iTBS is a form of repetitive transcranial magnetic simulation (rTMS), a non-invasive form of brain stimulation.
Methylphenidate (MPH)
Participants will be on methylphenidate clinically prior to the trial
Locations (1)
Sunnybrook Research Institute
Toronto, Ontario, Canada