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ZYNRELEF vs Continuous Catheter for Pain Management Following Shoulder Arthroplasty
Sponsor: Washington University School of Medicine
Summary
The purpose of this study is to determine if local intra-operative application of ZYNRELEF (topical medication) during shoulder replacement surgery improves pain control (as defined by opioid consumption after surgery) compared to the use of an interscalene block with catheter. This is a randomized clinical trial without blinding. Subjects will complete patient reported outcomes before and after surgery. Subjects will track their narcotic use, pain scores and pain satisfaction after surgery.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
86
Start Date
2026-02-14
Completion Date
2027-12
Last Updated
2026-02-19
Healthy Volunteers
No
Interventions
Zynrelef
ZYNRELEF
Bupivacaine
Interscalene block with continuous catheter pump
Locations (1)
Washington University
St Louis, Missouri, United States